Cardinals vs. Padres Prediction, Odds, Picks – July 26
Updated Jul. 26, 2025, 7:00 p.m. ET
The St. Louis Cardinals, led by Willson Contreras, are gearing up for the third game of a four-game series against Fernando Tatis Jr. and the San Diego Padres on Saturday at Busch Stadium. The Cardinals are favored in this matchup with odds of -145, while the underdog Padres are at +121, looking to spoil the party lisdepedgovph sign up. income level philippines St. Louis is also the favorite on the run line at -1.5 with +133 odds. aura yawi The total for the game is set at 9 runs.
Here’s everything you need to know from a betting perspective on the Cardinals-Padres game, including insights on the run line, moneyline, and total, plus expert picks. Stay updated with MLB on FOX Sports.
Cardinals vs. Padres Game Information & Odds
When: Saturday, July 26, 2025, at 7:15 p.m. ET
Where: Busch Stadium in St. Louis, Missouri
How to watch on TV: FDSMW and SDPA
Favorite | Moneyline | Underdog Moneyline | Total
Cardinals -145 | +121 | 9
Over Total Odds -116 | Under Total Odds -104 | Run Line Favorite -1.5 (+133) | Underdog Run Line Odds -159
Cardinals vs. Padres Prediction
Score Prediction: Cardinals 5, Padres 4
Total Prediction: Under 9 runs
Win Probabilities: Cardinals 53%, Padres 47%
Cardinals vs. Padres Betting Insights
The Cardinals have won 27 out of 49 games, or 55.1%, in which they’ve been favored this season. St. Louis holds an 11-4 record when playing as a favorite of -145 or more on the moneyline. Their chances of winning based on the moneyline imply a probability of 59.2%. On the other hand, the Padres have been underdogs in 50 games this year, clinching victory in 24 of those, resulting in a 48% win rate. This season, San Diego has won 12 out of 27 games when listed at +121 or worse. The odds suggest that the Padres have a 45.2% chance of winning this matchup.
Cardinals Recent Betting Performance
The Cardinals have been the moneyline favorite in six of their last 10 games, finishing with a record of 3-3. In their last 10 matchups, which all had set totals, the Cardinals and their opponents exceeded the run total five times. Their current ATS record over the past 10 games stands at 4-6-0.
Cardinals Recent Stats
Stat | Avg/Total
Record: 4-6
Runs Per Game: 4
Home Runs: 9
ERA: 5.19
K/9: 8.9
Cardinals Player Insights
Brendan Donovan leads the Cardinals with a batting average of .293, including nine home runs and 42 RBIs. He ranks 146th in home runs and 99th in RBIs among all players. Willson Contreras is also having a standout season, with 14 home runs and 61 RBIs, placing him 71st in home runs and 24th in RBIs in the league. Notably, Contreras has achieved a six-game hitting streak and is batting .351 over his last 10 games.
Alec Burleson has 18 doubles and 12 home runs, hitting .285, while Nolan Arenado brings in 15 doubles, a triple, 10 home runs, and 27 walks with a batting average of .239.
Cardinals Team Props
Hits O/U | Total Bases O/U | HR O/U | RBI O/U
Willson Contreras: 0.5 (-250) | 1.5 (+115) | – | 0.5 (+135)
Nolan Arenado: 0.5 (-270) | 1.5 (+115) | – | 0 top selling board games.5 (+170)
Masyn Winn: 0.5 (-260) | 1.5 (+115) | – | 0.5 (+185)
Jordan Walker: 0.5 (-220) | 1.5 (+140) | – | 0.5 (+190)
Ivan Herrera: 1.5 (+175) | 1.5 (+105) | – | 0.5 (+175)
Padres Recent Betting Performance
The Padres have competed as underdogs in five of their last 10 games, securing two wins in those encounters. When it comes to the total runs, the Padres have gone 4-6-0 in the over/under in their past 10 games. They have a record of 6-4-0 ATS in the same span.
Padres Recent Stats
Stat | Avg/Total
Record: 4-6
Runs Per Game: 3.7
Home Runs: 7
ERA: 3.18
K/9: 6.9
Padres Player Insights
Manny Machado leads the Padres with a .291 batting average, hitting 19 home runs and driving in 63 RBIs. He ranks 26th in homers and 20th in RBIs across the majors. Machado enters this game with a three-game hitting streak, batting .333 over his last five games. Fernando Tatis Jr. is batting .269 with 16 doubles, two triples, 17 home runs, and 55 walks. He ranks 44th in homers and 89th in RBIs among all major league hitters. Luis Arraez is maintaining a .287 average with 20 doubles and five home runs, while Xander Bogaerts is hitting .269 with 23 doubles and six home runs.
Padres Team Props
Hits O/U | Total Bases O/U | HR O/U | RBI O/U
Jackson Merrill: 0.5 (-270) | 1.5 (+120) | – | 0.5 (+140)
Xander Bogaerts: 1.5 (+195) | 1.5 (+120) | – | 0.5 (+185)
Manny Machado: 1.5 (+165) | 1.5 (-110) | – | 0.5 (+120)
Luis Arraez: 1.5 (+145) | 1.5 (+105) | – | 0.5 (+200)
Jose Iglesias: 1.5 (+200) | 1 sudan vs gilas score.5 (+135) | – | 0.5 (+210)
Want to know how the game will unfold? What are your predictions for the Cardinals and Padres matchup?